Zaltrap ® (ziv-aflibercept)

●      Brand Name: Zaltrap ®

●      Generic name: ziv-aflibercept

●     Uses: Treatment of colorectal cancer

●     How it works: Blocks growth in colon cancer

●     Most common side effects: High blood pressure, weight loss, decreased appetite, stomach pain, diarrhea, inflammation in the mouth, nose bleed, tiredness, protein in the urine, decrease functioning of the kidney, low white blood cell count, headache, difficulty speaking

●     Serious side effects: Chest pain caused by part of the heart muscle not getting enough oxygen, blood clot in the lungs, bleeding in the lungs, kidney damage, stroke, bleeding in the brain

●     Who cannot use this medication: Those who experience an allergic reaction to this medication

●     Dose: Available as 100mg/4ml and 200mg/8ml

○     4mg/kg of body weight through an intravenous injection over 1 hour every 2 weeks

●     Package Insert: http://products.sanofi.us/zaltrap/zaltrap.pdf

●     Reference: Micromedex Web site. http://www.thomsonhc.com.proxy.pba.edu/. Accessed October 1, 2012.