Stivarga® (regorafenib)

 

●     Brand Name: Stivarga® 

●     Generic name:  regorafenib

 

●     Uses:  Stivarga® is for adults with metastatic colorectal cancer who have previously been treated with other medications.

●     How it works:  Stivarga® slows the growth of tumor cells in the colon and eventually kills the tumor cells.  Stivarga® also helps to stop tumor cells from spreading into other parts of the colon.

 

●     Most common side effects:  Tiredness, weakness, fatigue, loss of appetite, diarrhea, swelling of mouth, throat, stomach, and intestines, weight loss, infections, and voice changes or hoarseness.

●     Serious side effects:  Liver problems, severe bleeding, skin problems, skin rash, high blood pressure, a tear in your stomach or intestines, wound healing problems, and a reversible condition that causes headache, confusion, seizures, and visual loss called leukoencephalopathy syndrome.

 

●      Who cannot use this medication:  Children cannot take Stivarga®

 

 

 

●      Dose:  Stivarga® is available as a 160 mg tablet that is taken by mouth once a day with a low-fat meal.

●      Package insert:  http://labeling.bayerhealthcare.com/html/products/pi/Stivarga_PI.pdf

 

●      References.

○      Stivarga website.  http://www.stivarga-us.com/index.html. Accessed September 28, 2012

○     MultiVu Multimedia & Broadcast PR.  http://www.multivu.com/mnr/57608-bayer-regorafenib-for-treatment-of-metastatic-colorectal-cancer. Accessed September 28, 2012.

○     Stivarga [package instert].  Wayne, NJ: Bayer HealthCarePharmaceuticals Inc.; 2012.